The Department of Psychology is delighted to announce the next talk of the Mind Meeting Seminar Series.
On Thursday 14th November, Prof. Jan Born (University of Tübingen) will give a talk entitled “About the memory function of sleep”.
When: Thursday 14th November, 15.30. The talk will be followed by a drinks reception.
Where: Wilhelm Wundt Room (note: change of location!), MPI for Cognitive and Brain Sciences Leipzig
You are very welcome to attend!
Whereas memories are optimally encoded and retrieved when the brain is awake, the consolidation and formation of long-term memory requires an offline mode of processing as optimally established only during sleep. Based on evidence from behavioral and neurophysiological studies in humans and rodents, I will consider the formation of long-term memory during sleep as an “active systems consolidation” process in which the repeated neuronal replay of representations originating from the hippocampus during slow-wave sleep (SWS) leads to a gradual transformation and integration of representations in neocortical networks. I will highlight three features of this process: (i) Hippocampal replay that, by capturing episodic memory aspects, drives consolidation of both hippocampus-dependent and non-hippocampus-dependent memory; (ii) brain oscillations hallmarking SWS and rapid-eye movement (REM) sleep that provide mechanisms to regulate both information flow across distant brain networks and local synaptic plasticity; and (iii) qualitative transformations of memories during systems consolidation resulting in abstracted, gist-like representations.
- M Friedrich, M Mölle, AD Friederici, J Born (2019). The reciprocal relation between sleep and memory in infancy: Memory‐dependent adjustment of sleep spindles and spindle‐dependent improvement of memories. Developmental science 22 (2), e12743
- N Niethard, HVV Ngo, I Ehrlich, J Born (2018). Cortical circuit activity underlying sleep slow oscillations and spindles. Proceedings of the National Academy of Sciences 115 (39), E9220-E9229
- A Sawangjit, CN Oyanedel, N Niethard, C Salazar, J Born, M Inostroza (2019). The hippocampus is crucial for forming non-hippocampal long-term memory during sleep. Nature 564 (7734), 109
Upcoming Mind Meeting talks: