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DoellerLab

Hippocampus as the storyteller: new study reveals how the brain makes sense of movies

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Our memories are what makes each of us unique, but this unique set of experiences is precisely what makes scientific study of memory difficult. The cumbersome nature of neuroimaging tools doesn’t help. MRI (Magnetic Resonance Imaging) scanners are so large and heavy that they are often positioned in place and the housing is built around them. So how can the scientists study the brain during everyday realistic memory tasks? We have decided to use movies in our pursuit of brain mechanisms of memory for events, the so-called “episodic memory”.

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Naomi de Haas wins Jan-Brouwer Thesis Price

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Naomi de Haas received the competitive Jan-Brouwer thesis prize 2016 for her master thesis “Navigating our memories: how episodes and space combine in the hippocampal formation”. The prize is being rewarded annually by the Royal Holland Society for Science (Koninklijke Hollandsche Maatschappij der Wetenschappen) in different categories of social sciences. Naomi’s thesis won the prize, which is worth 2000 Euro, in the category ‘humanities’.

http://www.khmw.nl/prijzen/prijs/jan-brouwer-scriptieprijzen/

New paper in Current Biology: Synchronized brain oscillations link distant brain regions that allow us to combine memories

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Humans have the remarkably ability to integrate information from multiple memories and infer indirect relationships. But how does our brain support this important function? In the latest study from our lab, we show that rhythmic brain waves, called theta oscillations, engage and synchronize the brain regions that support the integration of memories. The results were published in the journal Current Biology.
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New paper in Science: Alzheimer-disposition compromises brain system for spatial navigation

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Alzheimer’s patients suffer from severe memory loss and disorientation. An international research team led by Christian Doeller (Donders Institute, Radboud University, Nijmegen, The Netherlands) and Nikolai Axmacher (Ruhr-Universität Bochum, Germany) has now shown that a genetically increased risk for Alzheimer’s disease affects a brain region known as the “GPS” of the brain already in healthy young adults. The results were published in the journal “Science”.
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New paper on homologue regions for space and memory across species

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The 2014 Nobel prize in Medicine was awarded for the discovery of the brain’s GPS in the rodent entorhinal cortex. Despite numerous attempts in neuroscience and medicine in the past decades, the homologue entorhinal subregions in humans remained elusive. In this study, we combine high-field fMRI with novel connectivity methods to identify the corresponding areas in humans.
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DoellerLab on TV

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How come we can remember some things very well, while we often forget the rest? Christian Doeller, Sander Bosch and Silvy Collin set out to answer this question using fMRI neuroimaging for the Dutch television show “Katja’s Bodyscan”, starring television personality Katja Schuurman.

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